The morning everything changes Some children go to bed one way and wake up another. Obsessive-compulsive behaviours arrive at speed. Tics spike. Anxiety flares. Eating can abruptly narrow to a frighteningly small range - or stop altogether. That cliff-edge onset is the hallmark of Paediatric Acute-Onset Neuropsychiatric Syndrome (PANS) , a syndrome defined by the sudden arrival of OCD and/or severely restricted food intake, accompanied by additional neuropsychiatric symptoms

There is a moment after a brain injury when life splits into “before” and “after”. Not always dramatically, not always with a film-scene blackout. Sometimes it is subtler: a sentence that will not land, a light that feels too bright, a walk that suddenly requires concentration, a mood you do not recognise as your own. Nutrition cannot undo the event. But the biology that follows the event is not passive. The injured brain becomes a high-demand construction site that is short

When the lights flicker, the brain notices first If you want a single image to hold in your mind, make it this: your brain is a city that never sleeps, and mitochondria are its power stations. When those power stations struggle, symptoms can feel less like a label and more like a slow blackout, one neighbourhood at a time. Across conditions as different as Parkinson’s disease (PD), dementia, stroke, and motor neurone disease (MND), including amyotrophic lateral sclerosis (ALS